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Role for Inner Ring Deiodination Preventing Transcutaneous Passage of Thyroxine FERRUCCIO SANTINI, PAOLO VITTI, LUCA CHIOVATO, GIOVANNI CECCARINI, MARCO MACCHIA.Objective: (a) To compare the efficacy of low-activity (2 GBq; 54 mCi) 131I ablation using L-thyroxine withdrawal or rhTSH stimulation, and (b).

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Thyroxine (T4) is a tyrosine-based hormone produced by the thyroid glands. Thyroxine circulates throughout the body primarily bound to carrier proteins.After L-thyroxine (L-T4) replacement, bromocriptine treatment and OC withdrawn, TSH and Prl levels normalized, as well as the radiological pituitary image.